TLS Certificate Renewal FAQ

1. What changes are required if I renew the TLS Certificate on Clarity LIMS?

Scenario 1: TLS Certificate renewal signed by Public Certificate Authority or same Private Certificate Authority

No changes are required on the Illumina Run Manager Integration.

Scenario 2: TLS Certificate renewal signed by different Private Certificate Authority

The Illumina Run Manager Integration requires the following changes:

1. Access the Clarity LIMS Server via SSH and restart the Illumina Run Manager Integration Service using the following command.

   systemctl restart illumina_run_manager_integration

2. Disconnect all instruments from the Illumina Run Manager Integration following the instructions in the User Interaction Documentation.

   {% hint style="danger" %} Note: The instrument status may be shown as CONNECTED. However, to ensure that the Illumina Run Manager Integration works correctly after TLS Certificate renewal, disconnect the instrument from the Illumina Run Manager Integration and follow the remaining steps detailed below. {% endhint %}

3. Connect instruments again following the instructions in the User Interaction Documentation.

2. What changes are required if I renew the TLS Certificate on Illumina Run Manager?

Note: This section is only for users who are managing the Illumina Run Manager Certificate on their own. If you are letting Illumina Run Manager automatically renew its TLS Certificate, no changes are required.

Scenario 1: TLS Certificate renewal signed by Public Certificate Authority or same Private Certificate Authority

No changes are required on the Illumina Run Manager Integration.

Scenario 2: TLS Certificate renewal signed by different Private Certificate Authority

The Illumina Run Manager Integration requires the following changes:

1. Access the Clarity LIMS Server via SSH and restart the Illumina Run Manager Integration Service using the following command.

   systemctl restart illumina_run_manager_integration

2. Verify that the instrument is connected successfully on the Illumina Run Manager Integration UI - https://{Clarity LIMS server url}/irm. The status should be CONNECTED and LIMS Status should be ACTIVE.