> For the complete documentation index, see [llms.txt](https://help.claritylims.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.claritylims.illumina.com/instruments-and-integrations/other-release-notes/miseqdx-v1.5.0-release-notes.md).

# MiSeqDx v1.5.0

* MiSeq Operating Software (MOS) v1.1.7
* Real-Time Analysis (RTA) v1.16.18
* MiSeq Reporter Software (MRS) v2.2.31.1

## Features to note for this release

The **Illumina MiSeqDx Integration Package v1.5** includes support for both MiSeqDx **Research** mode and **Diagnostic** mode.

* For **Diagnostic** mode, this integration package supports the following three kits: **CF 139-Variant Assay, CF Clinical Sequencing Assay**, and **Universal Kit.**
* For **Research** mode, the **Illumina MiSeq Integration Package v5.3** is also included.

## New features

This release supports the integration between BaseSpace Clarity LIMS and the MiSeqDx instrument. At a high level, this integration includes the following features:

* In **CF 139-Variant Assay** and **Universal Kit** workflows, indexes are automatically placed on samples when running the **PCR Amplification** step in the **Library Prep** protocol.
* Key metrics are parsed back into LIMS following the completion of primary analysis on the instrument.
* Variant call files are attached to the **Variant Calling** step in the LIMS, individually for each sample and one combined file for all the samples together.

## Defects fixed

None

## Known issues

This release contains the following known issues, which are prioritized for a later release:

* Following a sequencing run, user must wait until the run report is automatically generated and attached before finishing the **MiSeqDx Run** step. If user completes the step before these events occur, they cannot return to the step and regenerate the report.
* The metrics parsed back into the LIMS for %Bases Q30 R1 and R2 are not consistent with Sequencing Analysis Viewer.


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