# NextSeq 1000/2000 v2.1.1

The following release notes detail the key changes to software components for the Clarity LIMS NextSeq 1000/2000 Integration Package v2.1.1.

This update addresses Apache log4j vulnerabilities found in prior versions of the NextSeq 1000/2000 Integration Package.

## Compatibility

This version of the integration package is compatible with the following software:

* Clarity LIMS v5.3 and later
* NextSeq 1000/2000 Instrument Control Software v1.1 and later (up to v1.4 only)
* If you are currently using Clarity LIMS NextSeq1000/2000 Integration v.2.1.0, contact Illumina Support to update to v2.1.1.

## Defect Repairs

This is a patch release to address the following Apache log4j vulnerabilities:

* CVE-2021-44228
* CVE-2021-45046
* CVE-2021-45105
* CVE-2021-44832

## Known Issues

* A sequencing run error is triggered when instrument disk space is full. This error causes RunParameters.xml to be empty and the run event is not processed on Clarity LIMS.
* This error is unlikely to occur as pre-run checks on the instrument check for sufficient disk space before run is started.

## Limitations

For the demultiplexing information in the Sample Details table to display correctly, the following conditions must be met:

* The DRAGEN version must be earlier than v3.9.3.
* The samples in the run must not repeat.
* The run must be for the single lane flow cell (P1 or P2).