# NextSeq 1000/2000 v2.2.0

These Release Notes describe the key changes to software components for the Clarity LIMS NextSeq 1000/2000 Integration Package since version 2.1.

This is an optional software update for customers interested in the features available with this release.

If upgrading from a version prior to v2.1, review the release notes for v2.1 for a list of features and bug fixes introduced in that version.

## Compatibility

This version of the integration package is compatible with the following software:

* Clarity LIMS v5.3 and later
* NextSeq 1000/2000 Instrument Control Software (NCS) v1.1 through 1.4.

## New Features

Features provided with this release of the integration package are as follows:

* Support for Clarity LIMS v6.0.
* Fixes to address the following Apache log4j vulnerabilities:
  * CVE-2021-44228
  * CVE-2021-45046
  * CVE-2021-45105
  * CVE-2021-44832
* Tech refresh to upgrade third party libraries.
* Inclusion of non-PhiX control samples in v2 sample sheet.

## Defect Repairs

None.

## Known Issues

* A sequencing run error is triggered when instrument disk space is full. This error causes RunParameters.xml to be empty and the run event is not processed on Clarity LIMS.
* This error is unlikely to occur as pre-run checks on the instrument check for sufficient disk space before run is started.

## Limitations

For the demultiplexing information in the Sample Details table to display correctly, the following conditions must be met:

* The DRAGEN version must be earlier than v3.9.3.
* The samples in the run must not repeat.
* The run must be for the single lane flow cell (P1 or P2).