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NextSeq 1000/2000 v2.2.0

These Release Notes describe the key changes to software components for the Clarity LIMS NextSeq 1000/2000 Integration Package since version 2.1.

This is an optional software update for customers interested in the features available with this release.

If upgrading from a version prior to v2.1, review the release notes for v2.1 for a list of features and bug fixes introduced in that version.

Compatibility

This version of the integration package is compatible with the following software:

  • Clarity LIMS v5.3 and later

  • NextSeq 1000/2000 Instrument Control Software (NCS) v1.1 through 1.4.

New Features

Features provided with this release of the integration package are as follows:

  • Support for Clarity LIMS v6.0.

  • Fixes to address the following Apache log4j vulnerabilities:

    • CVE-2021-44228

    • CVE-2021-45046

    • CVE-2021-45105

    • CVE-2021-44832

  • Tech refresh to upgrade third party libraries.

  • Inclusion of non-PhiX control samples in v2 sample sheet.

Defect Repairs

None.

Known Issues

  • A sequencing run error is triggered when instrument disk space is full. This error causes RunParameters.xml to be empty and the run event is not processed on Clarity LIMS.

  • This error is unlikely to occur as pre-run checks on the instrument check for sufficient disk space before run is started.

Limitations

For the demultiplexing information in the Sample Details table to display correctly, the following conditions must be met:

  • The DRAGEN version must be earlier than v3.9.3.

  • The samples in the run must not repeat.

  • The run must be for the single lane flow cell (P1 or P2).

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